Brief Communications Rhythmically Active Enkephalin-Expressing GABAergic Cells in the CA1 Area of the Hippocampus Project to the Subiculum and Preferentially Innervate Interneurons
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چکیده
Pablo Fuentealba,1 Ryohei Tomioka,1,2 Yannis Dalezios,1,3,4 László F. Márton,1,5 Michele Studer,6 Kathleen Rockland,2 Thomas Klausberger,1 and Peter Somogyi1 1Medical Research Council Anatomical Neuropharmacology Unit, Department of Pharmacology, University of Oxford, Oxford OX1 3TH, United Kingdom, 2Laboratory of Cortical Organization and Systematics, RIKEN Brain Science Institute, Wako, Saitama 351-0198, Japan, 3Department of Basic Sciences, Faculty of Medicine, University of Crete, GR-71003 Heraklion, Greece, 4Institute of Applied and Computational Mathematics, Foundation of Research and Technology–Hellas, GR-71110 Heraklion, Greece, 5Neural Systems Research Group, Sapientia-Hungarian University of Transylvania, Targu Mures, Romania, and 6Telethon Institute of Genetics and Medicine, 80131 Naples, Italy
منابع مشابه
Rhythmically active enkephalin-expressing GABAergic cells in the CA1 area of the hippocampus project to the subiculum and preferentially innervate interneurons.
Enkephalins (ENKs) are endogenous opioids that regulate synaptic excitability of GABAergic networks in the cerebral cortex. Using retrograde tracer injections in the subiculum, we identified a hippocampal population of ENK-expressing projection neurons. In situ hybridization for GAD shows that ENK-expressing cells are a small GABAergic subpopulation. Furthermore, by extracellular recording and ...
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تاریخ انتشار 2008